Lituo - Atop Beauty Clinic
GangNam, Seoul, Korea ★★★★★ 4.9
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#SlowAging #RejuvenationInjection #HomograftDermis

Re2O

A next-generation skin booster composed of ECM components naturally found in the human body.

REAL HUMAN SKIN

A first in the aesthetic market — direct replenishment of ECM components (the structural framework of the skin) derived from real human skin tissue.

Excellent biocompatibility

Does not alter the body’s native ECM matrix structure, allowing seamless interaction with existing cells.

Fill? No. Revive? Yes.

Rather than simply adding volume, it delivers direct skin regeneration by injecting actual ECM components — including collagen, elastin, and hyaluronic acid.

REAL HUMAN SKIN

A first in the aesthetic market — direct replenishment of ECM components (the structural framework of the skin) derived from real human skin tissue.

Excellent biocompatibility

Does not alter the body’s native ECM matrix structure, allowing seamless interaction with existing cells.

Fill? No. Revive? Yes.

Rather than simply adding volume, it delivers direct skin regeneration by injecting actual ECM components — including collagen, elastin, and hyaluronic acid.

Elravie RE20 directly replenishes real human skin ECM for true, structural skin restoration.

Elravie RE20 is the first in Korea to refine actual human skin–derived ECM components into microparticles and inject them directly into the dermis. It is a next-generation skin booster approved by the FDA, MFDS, and AATB (American Association of Tissue Banks). All immunogenic elements, such as cells and lipids that may trigger immune reactions, are removed — leaving only purified ECM. By preserving the body’s native three-dimensional matrix structure, it stably integrates into the skin and promotes natural cellular regeneration. As a result, patients can expect multiple benefits, including subtle volume enhancement, pore refinement, improved skin texture and density, enhanced deep hydration, and increased radiance.

Is collagen the only way to improve aging?

yet, Beyond simple collagen
It's time to PAY ATTENTION!To ECM.

Collagen is a single structural component that supports the skin, and collagen alone cannot fully create an optimal “regenerative environment.” In contrast, ECM is the complete structural framework of skin tissue — including collagen — that supports cells and maintains the integrity of the tissue architecture. In other words, ECM is a comprehensive dermal matrix composed of collagen and multiple regenerative components essential for true skin restoration.

From your XNUMXs onward, ECM components begin to decline noticeably.

Direct [ ECM replenishment ]
for seamless, thorough slow aging.

For skin aged by ECM depletion,

Elravie RE20 directly replenishes real human skin–derived ECM.

Collagen

Elastin

GF (growth factor)

Hyaluronic Acid

Fibronectin

Laminin

Tenascin

MMPS

[ A New Dimension ] of booster,
Elravie Re2O.

While first- to fourth-generation skin boosters were derived from sources such as trout, salmon, or porcine extracts — or worked by stimulating the skin’s own regenerative synthesis — LITUO represents a new-generation, next-level skin booster that directly replenishes real human ECM into the skin.

The process of skin [ coming back to life ] with Elravie RE20 Skin Booster.

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STEP_01

Dermal imbalance caused by collagen loss due to aging.

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STEP_02

Direct injection of high-purity, human-derived ECM into the dermal layer.

img01

STEP_03

As skin density improves, the skin’s structural integrity is restored, allowing it to regenerate stronger and healthier from within.

Immediate volume, plus tone / texture / radiance
and beyond — Comprehensive Multi-Layer Care.

Over time, results build progressively — step by step.

Immediately after treatment

  • Instant micro volume

3~5 days later

  • Improved blood circulation
  • Improvement of skin barrier and thickness

1~2 weeks later

  • Pore Reduction
  • Improved skin texture
  • Improvement of fine wrinkles
  • Autologous collagen regeneration

3~4 weeks later

  • Improvement of redness
  • Improvement of freckles/blemishes
  • Improved skin resilience
  • Volume boost

Clinical data doesn’t lie — Elravie RE20 proves its results with clear, measurable metrics.

Increased collagen

2.9Belly

Increased elastin

3.2Belly

Beyond its collagen-stimulating effects and excellent longevity, Elravie RE20 has demonstrated sustained results — with 2.9× increased collagen and 3.2× increased elastin density confirmed even at 6 months.

* Characterization and tissue incorporation of cross-linked
human acellular dermal matrix (Ju Hee Lee, Hyung Goo Kim,
Won Jai Lee/16 December 2014)

With real skin-derived components,
it delivers a natural texture and feel.

Improve pore size

Improvement of freckles/blemishes

Improved skin texture/density

Improve skin radiance

* Data after 1 month of Lituo + HA mixed treatment
* Measurement and Evaluation Agency: Global Medical Research Center

As it is derived from real human skin ECM, it offers excellent biocompatibility.

Through its proprietary AlloClean Technology, Elravie RE20 significantly reduces residual DNA content while preserving the body’s native ECM matrix structure. This allows seamless interaction with surrounding cells after injection, enabling the safe formation of newly regenerated ECM.

What is AlloClean Technology?

L&C BIO’s proprietary human tissue processing technology preserves the tissue’s native three-dimensional structure while removing cellular components and immune rejection–triggering factors within the tissue.

[ Low risk of lumpiness and nodules ],
for confident, worry-free treatment with RE20.

Administered into the deep dermal layer, resulting in a very low risk of surface irregularities (embossing).

By injecting real human skin–derived ECM, it integrates naturally into the skin
as if grafted
, resulting in a very low risk of nodule formation.

RE20 Treatment Areas.

Same procedure, different results
RE20 B&A

Before and after photos of Lituo
Before and after photos of Lituo

Q&A
REXNUMX l Frequently Asked Questions.

They say they use the ECM of actual human skin.
Is it safe?
Elravie ReXNUMX is manufactured from human skin tissue donated under the strict standards of the AATB (American Association of Tissue Banks). Through a decellularization process, cellular components and potential immune-triggering factors are removed while preserving the skin’s native structure, ensuring both safety and biocompatibility. It is also a product approved by the FDA and MFDS.
How is the pain?
The main component of Elravie ReXNUMX, human-derived ECM, consists of extremely fine particles with low viscoelasticity. Because it creates minimal resistance (injection pressure) when administered into the skin, the procedure involves relatively little discomfort.
The biggest difference between Elravie ReXNUMX and the existing skin booster..
What is it?
While conventional skin boosters primarily work by stimulating skin cells to “induce” the production of autologous collagen, Elravie ReXNUMX directly replenishes acellular allogeneic dermis — in other words, actual ECM — into the dermal layer, providing a more stable regenerative environment and restoring the skin’s structural integrity.

RE20
is recommended for...

  • Those who want slow aging.
  • Those who need fundamental dermal remodeling.
  • Those who are concerned about their rough and dry skin.
  • Those who need to get rid of wrinkles.
  • Those who have off oil and moisture balance so their pores are enlarged with excessive oil production.
  • Those who have uneven skin tone.
  • Those who are sensitive to pain.
  • Those who want a skin booster with less downtime.